The inventor in his shed is messing about with the fabric of reality. His wife objects

Edward, the woman’s significant other, is a backyard scientist.

He is somehow able, with his rudimentary equipment, to modify reality itself, demonstrated by the bizarre alterations of the woman and her surroundings in the intermediate panels as she attempts to get to the shed in the back yard.

She then goes into his shed and tells him off.

Part of the joke is that reality goes through bizarre and unexpected changes. The other part of the joke is that a man with the power of a god is being told off by his relatively powerless wife.